Youthful skin starts within
Sculptra® Aesthetic works subtly and gradually over time for a more youthful-looking appearance. Unlike hyaluronic acid (HA) fillers, Sculptra Aesthetic helps stimulate your skin’s own natural collagen production to help restore its inner structure and increase facial volume that has been lost to aging.1-3 Sculptra Aesthetic is intended for use in people with healthy immune systems as a one-time treatment regimen of up to four injection sessions that are scheduled about three weeks apart.
80% of users were still satisfied with their treatment results 25 months after their last injection.
*Clinical study ended at 25 months.
†User = Clinical trial subject
Collagen by the numbers
Collagen is a key structural component of smooth, healthy-looking skin. As you age, your body’s collagen production decreases. In fact, you lose about 1% of collagen per year after the age of 18.5 This is when you may start to notice the formation of wrinkles. Luckily, Sculptra Aesthetic can help, even if decades of collagen loss have already occurred.
You lose about 1% of collagen per year after the age of 18.5
What Is Sculptra® Aesthetic?
Address an underlying cause of facial aging, not just the symptoms
Between the nose and mouth
(nasolabial folds), commonly called
In the lines framing your mouth, also
known as “marionette lines” or “laugh lines”
On your chin
Sculptra Aesthetic is an FDA-approved injectable that helps gradually replace lost collagen — an underlying cause of facial aging — for results that can last more than two years.*
It’s used to correct shallow to deep facial wrinkles and folds
*Clinical study ended at 25 months.
Sculptra Aesthetic should not be injected into the blood vessels as it may cause vascular occlusion, infarction or embolic phenomena. Sculptra Aesthetic should not be injected into the red area (vermillion) of the lip or in the periorbital area.
Why should you choose Sculptra Aesthetic?
Real results that last
Not all treatments or injectables are created the same. Some target different areas of the face, and, more importantly, produce different effects.
Traditional collagen creams purport to deliver collagen that is absorbed by the skin. However, collagen molecules are too large to penetrate the dermis. So, in actuality, most of these treatments include vitamins and hold moisture, making them suitable moisturizers that can briefly improve skin’s appearance.
Collagen dietary supplements are meant to facilitate the production of collagen within the body. However, collagen is a protein that, when ingested, is broken down by the digestive system. The results for these types of treatments are inconclusive.
Toxins work by temporarily weakening muscles, typically in the forehead, to minimize frown lines. Results appear within a couple of days and can last up to a couple of months.
Sculptra Aesthetic may stimulate collagen growth which helps to restore facial volume and the look of fullness to wrinkles and folds over time.
Results appear gradually over the treatment regime (typically three injections over the course of three to four months) and can last up to two years.*
*Individual results and treatment sessions may vary. The clinical trial ended at 25 months.
Fillers are liquid or gel substances, like hyaluronic acid or bovine or porcine collagen, that diminish lines by pushing up the dermis space beneath wrinkles and creases. Results appear immediately and can last up to several months.
Collagen stimulators are used to diminish facial wrinkles by helping to restore the deep, underlying structure of the skin. Results appear gradually over the treatment regime (typically three injections over the course of three to four months) and can last up to two years.*
As a poly-L-lactic acid (PLLA) collagen stimulator, Sculptra Aesthetic is different. It works with your body within the deep dermis, rather than topically, to help revitalize collagen production and help restore your skin’s inner structure and volume.1-3 As the Sculptra Aesthetic PLLA microparticles are absorbed, they help stimulate collagen production. Rebuilt collagen strands begin gradually helping to restore facial volume4 and the look of fullness to wrinkles and folds.
*Individual results and treatment sessions may vary. Clinical trial ended at 25 months.
If you want to appear more youthful-looking — without appearing like you’ve had work done — then chances are Sculptra Aesthetic may be a good choice for you.
How does Sculptra Aesthetic work?
Slow and steady strength
Sculptra Aesthetic is made with a biocompatible, biodegradable, synthetic material called poly-L-lactic acid, which is gradually and naturally absorbed by the body and helps to rebuild lost
collagen through a series of treatments administered by a trained specialist.
The specialist injects treatment within the deep dermis, where strands of collagen support your skin’s structure. Over time, Sculptra Aesthetic helps the body reproduce lost collagen. On average, three injection appointments are
needed over a period of a few months. The number of injection appointments and the number of injections per appointment vary from person to person, depending on how much collagen has been lost.
- Stein P, Vitavska O, Kind P, Hoppe W, Wieczorek H, Süchurer NY. The biological basis for poly-L-lactic acid-induced augmentation. J Dermatol Sci. 2015;78(1):26–33.
- Goldberg D, Guana A, Volk A, Daro-Kaftan E. Single-arm study for the characterization of human tissue response to injectable poly-L-lactic acid. Dermatol Surg. 2013;39(6):915–922.
- Sculptra Aesthetic injectable poly-L-lactic acid. Instructions for Use. Galderma Laboratories. 2016.
- Gogolewski S, Jovanovic M, Perren SM, Dillon JG, Hughes MK. Tissue response and in vivo degradation of selected polyhydroxyacids: polylactides (PLA), poly(3-hydroxybutyrate) (PHB), and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHB/VA). J Biomed Mater Res. 1993;27(9):1135–1148.
Click here for patient information about Sculptra® Aesthetic (PDF)
Important Safety Information
Indication: Sculptra® Aesthetic (injectable poly-L-lactic acid) is indicated for use in people with healthy immune systems as a single regimen for the correction of shallow to deep nasolabial fold contour deficiencies and other facial wrinkles in which deep dermal grid pattern (cross-hatch) injection technique is appropriate.
Sculptra Aesthetic should not be used by people that are allergic to any ingredient of the product or have a history of keloid formation or hypertrophic scarring. Safety has not been established in patients who are pregnant, lactating, breastfeeding, or under 18 years of age.
Sculptra Aesthetic has unique injection requirements and should only be used by a trained physician. Contour deficiencies should not be overcorrected because they are expected to gradually improve after treatment.
Sculptra Aesthetic should not be injected into the blood vessels as it may cause vascular occlusion, infarction or embolic phenomena. Use at the site of skin sores, cysts, pimples, rashes, hives or infection should be postponed until healing is complete. Sculptra Aesthetic should not be injected into the red area (vermillion) of the lip or in the peri-orbital area.
The most common side effects after initial treatment include injection site swelling, tenderness, redness, pain, bruising, bleeding, itching and lumps. Other side effects may include small lumps under the skin that are sometimes noticeable when pressing on the treated area. Larger lumps, some with delayed onset with or without inflammation or skin discoloration, have also been reported.
Sculptra Aesthetic is available only through a licensed practitioner. View the complete Instructions for Use.
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